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Dapagliflozin: A molecule for type-2 diabetes mellitus

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Review Article

Author Details : Ravinandan A P*, Hunsur Nagendra Vishwas, Shashank S Hosur, Mohammed Mustafa G. , Kavya H.B.

Volume : 9, Issue : 4, Year : 2022

Article Page : 156-162

https://doi.org/10.18231/j.ijpca.2022.029

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Abstract

Dapagliflozin which is also known as Farxiga in the US and Forxiga in the EU is a drug which was developed by Bristol-Myers Squibb in partnership with Astra Zeneca. It is also available in Oxra and it is marking by Sun Pharmaceutical Industries Ltd. It contains the active substance Dapagliflozin which is the second member of selective sodium glucose co-transporter-2 (SGLT-2) inhibitor and it is the first group among oral anti-diabetic agents which are independent of insulin secretion. The drug Dapagliflozin shows the action of reducing the blood glucose by preventing the reabsorption of glucose at the renal proximal tubule and avoids insulin resistance. It is a new molecule that helps in maintaining the glycemic control either in mono therapy or combinational therapy or add on therapy. This is a review article which summarizes the details of Dapagliflozin.

Keywords: Type2 Diabetes Mellitus, Dapagliflozin, Selective Sodium Glucose Co, Transporter2 (SGLT2) Inhibitor

How to cite : Ravinandan A P, Vishwas H N, Hosur S S , Mohammed Mustafa G., H.b. K, Dapagliflozin: A molecule for type-2 diabetes mellitus. Int J Pharm Chem Anal 2022;9(4):156-162

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