Gymnema sylvestre is a perennial woody vine native to the tropical forests of India and Africa. Widely recognised in Ayurvedic medicine as "Gurmar" or “sugar destroyer,” this plant has gained attention for its antidiabetic, hypolipidemic, antioxidant, anti-inflammatory, antimicrobial, and hepatoprotective properties. This review consolidates existing scientific knowledge on the botanical description, phytochemical constituents, traditional uses, pharmacological effects, and therapeutic potential of G. sylvestre, emphasising its role in diabetes management. Recent research trends, formulations, and prospects in pharmacognosy and herbal medicine are also discussed.